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Sunday, November 6, 2011

HIV Medication Fact Sheets. Easy to Use Fact Sheets

HIV Medication Fact Sheets
Easy to Use Fact Sheets

This area of our site is provided as a quick reference only. We strongly urge you to discuss medication concerns with your physician.

Important Fact! - Remember to always take medications exactly as prescribed and not to change or stop your medications without first speaking with your physician.

Integrase Inhibitors
Integrase is an enzyme that does what the name implies; it integrates HIV genetic material into the DNA of human CD4 cells making it possible for the infected cell to make new copies of HIV. By interfering with integrase during the HIV life cycle, the integrase inhibitors prevent HIV genetic material from integrating into the CD4 cell, thus stopping viral replication.

Entry Inhibitors
Entry Inhibitors work by interfering with HIV's entry into the CD4 cell. By interfering during the entry phase of the HIV life cycle, entry inhibitors block HIV replication.

Non-Nucleosides Reverse Transcriptase Inhibitors (NNRTI's)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) work by binding tightly to the enzyme reverse transcriptase which prevents viral RNA from converting to the viral DNA that infects healthy cells.

Nucleotide Analogs
Like the nucleoside analogues such as Retrovir (AZT) and Videx EC (didanosine), nucleotide analogues inhibit reverse transcriptase. However, they are active in their native form, unlike nucleosides that only work in cells that have the machinery to activate the drug by a process called phosphorylation. This means that the nucleotide analogues may be active against HIV in a wider variety of infected cells.

Protease Inhibitors (PI's)
Protease Inhibitors stop HIV replication by preventing the enzyme protease from cutting the virus into the shorter pieces that it needs to make copies of itself. Incomplete, defective copies are formed which can't infect cells.

Nucleoside Reverse Transcriptase Inhibitors (NRTI's)
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) work by being incorporated into the viral DNA, making it ineffective. These compounds suppress replication of retroviruses by interfering with the reverse transcriptase enzyme. The nucleoside analogs cause premature termination of the proviral (viral precursor) DNA chain.

Combination Medications
In an effort to improve medication adherence and to make it easier to take your medications each day, many medications are combined into one pill or capsule. Fewer pills each day has been shown to improve adherence which we know improves the effectiveness of HIV regimens.

HIV Medications. How Much Do They Cost?

HIV Medications
How Much Do They Cost?

It's no secret, HIV medicines are very expensive. For most, insurances, drug assistance programs, or community resources pay most of the cost. But what about those who are not so fortunate. While we all know HIV medications are very costly, not taking them can be even more costly. Have you ever wondered what those HIV medications you are taking cost each month? The following table will give you an idea just how pricey HIV medications can be.

Important Fact! - Prices will vary depending where they are purchased and how they are paid for. Mail-order pharmacies may be cheaper than your neighborhood pharmacy for instance. The Linkprices given here are for estimates and comparisons only. Check with your local pharmacy and your drug insurance to find out just how much your HIV medications will cost you.

COST PER MONTH (estimates) - Medication Fact Sheets
Agenerase $772
Aptivus $1117.50
Combivir $752.64
Crixivan $570.96
Emtriva $347.11
Epivir 300mg $347.11
Epzicom $813.55
Fortovase $263.35
Fuzeon $2315.40
Hivid $273.00
Invirase $748.50
Kaletra $796.26
Lexiva $658.99
Norvir $321.46
Rescriptor $316.35
Retrovir $405.59
Reyataz $892.91
Sustiva 600mg $499.43
Trizivir $1164.35
Truvada $867.99
Videx EC 400mg $346.04
Viramune $442.45
Zerit $385.88
Ziagen $466.44

Source: Test Positive Aware Network; "Annual HIV Drug Guide"; 2006.